Seton Hotel is located in New York City near: The hotel is located in a safe residential part of Manhattan conveniently located near many New York attractions and landmarks, including:

- The UN
- Grand Central Station
- The Empire State Building
- The Chrysler Building
- The Pan Am Building (Met-Life Building)
- 5th Avenue Shopping
- Times Square
- Macy's and Herald Square
- 57th Street Boutiques
- 47th Street Diamond District
- Rockefeller Center
- Jacob Javits Convention Center

Subway Information:

4, 5, 6, or 7 Trains to 42nd Street - Grand Central Station stop